Review shows HRT does not impact dementia risk
A review published in The Lancet Healthy Longevity has shown that menopause hormone therapy – also known as hormone replacement therapy (HRT) – neither increases nor decreases a post-menopausal woman’s risk of developing mild cognitive impairment (MCI) or dementia.
The research, commissioned by the World Health Organisation (WHO) and led by University College London with support from the University of Exeter, comprised a systematic review and meta-analysis of data from more than one million women.
Professor Chris Fox, from the University of Exeter Medical School, says:
“The role of menopause hormone treatment and relationship to dementia is a worry for many women. But our state-of-the-art review indicates there is no evidence that menopause hormone treatment reduces or increases the risk of dementia. When deciding whether to take menopause hormone treatment, reducing one’s risk of dementia should not be part of that decision.”
Read the review here: https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(25)00122-9/fulltext
Read more from the University of Exeter here: https://news.exeter.ac.uk/faculty-of-health-and-life-sciences/menopause-hormone-therapy-does-not-appear-to-impact-dementia-risk/